Introduction: What is N-Piperidinyl Etonitazene?

N-Piperidinyl Etonitazene is classified as a novel opioid. A novel opioid is a Novel Psychoactive Substance (NPS) with one NPS arriving on the market each week. These are chemicals made in a laboratory (usually in China) and shipped to the United States for consumption.

Structurally similar compounds include etonitazene, metonitazene, and isotonitazene. N-piperidinyl Etonitazene is a chemical compound that was created in the 1950s by researchers at Pfizer. Data suggest that this group of analogues can have potency similar to or greater than fentanyl.

Recent in vitro data suggest that N-piperidinyl etonitazene is slightly less potent than etonitazene but more potent than fentanyl (unpublished data from M. Vandeputte and C. Stove). N-Piperidinyl Etonitazene is not explicitly scheduled in the United States; however, etonitazene and isotonitazene are Schedule I substances.

N-Piperidinyl Etonitazene will usually appear as a crystalline powder. 

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The Risks of Using N-Piperidinyl Etonitazene

Novel opioids have been reported to cause psychoactive effects similar to heroin, fentanyl, and other opioids. Novel opioids have also caused adverse events, including death. Like most opioids, Narcan can reverse an overdose.

Intelligence Analysis

This is a drug that may come up occasionally, but will be rarely seen, if at all, by most officers. With that said, there will more than likely be overdoses in the United States with this drug because of its potency. Officers should be aware of it for this reason alone. 

 



Author: Keith Graves
Keith is a retired Police Sergeant, working his entire 29 year career in the San Francisco Bay Area. Keith is a recipient of the prestigious California’s Narcotics Officer of the Year Award and is a prior winner of MADD’s California Hero Award. He has years of experience as a Narcotics Detective and a Narcotics Unit Supervisor and is a Drug Recognition Expert Instructor (IACP #3292). Keith has developed several courses for the Department of Defense, California Narcotics Officers Association, and California POST, and numerous police agencies and private corporations. Keith has held other assignments besides narcotics including Training Sergeant, Patrol Sergeant, COPPS Officer, Traffic Officer, and 20 years as a SWAT Team member and Sniper Team Leader. Keith has taught thousands of officers and businesses around the world about drug use, drug trends, compliance training and drug investigations. Keith is also the founder of Christian Warrior Training, where he provides free resources and training to church security ministries. He is recognized as an international drug expert and has testified as an expert in court proceedings on drug cases, homicide cases and rape prosecutions. Keith earned a BA in Business Management from Saint Mary’s College of California and a MA in Criminal Justice. Keith is the Founder and President of Graves & Associates, a company dedicated to providing drug training to law enforcement, the Department of Defense, and private industry internationally. You can follow Keith on social media on Facebook (DopeCop and DrugEnforcementCops), twitter (DopeCop) and Instagram (DrugEnforcementCops).

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